The proposed mechanism is through basement membrane deposition of immune complexes, predominantly IgG and C1q, which leads to a diffuse glomerular capillary leak, non-selective proteinuria, and reduced renal function [6]. In this case, IgG and C1q deposition is observed, further differentiating it from autoimmune diseases like lupus, which present with deposition of IgA, IgG, IgM, C3, and C1q. This evidence concerns the gene CD40LG and systemic lupus erythematosus.