Two genes, MTC01P12 (Log2FC = 4.67, pAdj = 0.007) and HLA-DRB5 (Log2FC = 9.14, pAdj = 0.001) were found to be significantly upregulated in the depression group when compared with controls (Fig. 2B). The gene discussed is HLA-DRB5; the disease is depressive symptom measurement.