TNF and endocrine system disorder: Figures 7A and 7B showed the top 50 enriched pathways, which can be divided into four categories: cellular processes (cell growth and death, cell communication), organism systems (endocrine system, immune system, nervous system), human diseases (tumors, cardiovascular diseases, infectious diseases, and endocrine diseases), and signal transduction (HIF-1 signaling pathway, PI3K-Akt signaling pathway, TNF signaling pathway, MAPK signaling pathway, and VEGF signaling pathway).