DNMT3B and neoplasm: In the first GSEA analysis, we compared the DNMT3B+ tumours (with downregulation of GATA3 expression and high levels of methylation in the promoter region of the gene—this group was named GATA3–METH) with the control group of tumour samples in which DNMT3B was not ectopically activated and no genetic alteration for GATA3 was found (the control group was named GATA3–CTRL).