Since rs1071644 is a functional SNP and PLCG2 has been previously implicated in AD by genetics (Bellenguez et al., 2022; Dalmasso et al., 2019; Jansen et al., 2019; Kleineidam et al., 2020; Magno et al., 2019; Olive et al., 2020; Sims et al., 2017; Strickland et al., 2020; van der Lee et al., 2019), we tested whether rs1071644 is associated with AD risk. Here, PLCG2 is linked to Alzheimer disease.