First, we characterized p53 dynamics in response to different doses of these stimuli in a previous established small cell lung carcinoma cell line A549 expressing wild type p53 fused with the mVenus fluorescent protein (Chen et al., 2013) using live-cell time-lapse microscopy (Figures 1C–G; Supplementary Figures S1A, B). This evidence concerns the gene TP53 and small cell lung carcinoma.