LYST and cancer: In contrast, a comparative study using gallic acid functionalized copper oxide nanoparticles (GaCuO) loaded with paclitaxel (PTX) showed superior ROS-mediated cytotoxicity in MCF _7 cells, with the kappa carrageenan and folic acid coatings enhancing targeted delivery and improved biocompatibility.118 Carrageenan-cholesterol (CRG-CHS) and folic acid-modified carrageenan-cholesterol (FA-CRG-CHS) amphiphilic conjugates were synthesized as nano micelle carriers for the intracellular delivery of the anti-cancer drug doxorubicin (DOX).