In clinical studies, XYSJW has demonstrated a significant ability to reduce the levels of IFN-γ, IL-2, and IL-6 while increasing IL-10 levels in patients with Hashimoto’s thyroiditis and chronic lymphocytic thyroiditis, thereby regulating the Th1/Th2 balance (Zhang Y. et al., 2021). The gene discussed is IFNG; the disease is Hashimoto thyroiditis.