It inhibits the expression of Th1-type cytokine IFN-γ and local Th17-type cytokine IL-17, corrects the imbalance of Th1/Th2 and Th17/Treg, and reduces the severity of Hashimoto’s thyroiditis in mice (Du et al., 2022). The gene discussed is IL17A; the disease is Hashimoto thyroiditis.