The tumor was classified as nuclear grade 3, histological grade 3, estrogen receptor 0%, progesterone receptor 0%, human epidermal growth factor receptor-2: 0 (immunohistochemistry score), Ki-67: >20% (hot spot: 90%), and tumor-infiltrating lymphocytes score: 10%–20% (Fig. 3).3) The gene discussed is MKI67; the disease is neoplasm.