CXE is proven to suppress NO, pro-inflammatory (IL-6, IL-1β, and LDH), and apoptosis genes (Casp-9, Casp-3, and JNK) in APAP-mediated liver cells while increasing the expression of an anti-inflammatory agent (IL-10), which can be a potent target for liver disease treatment. The gene discussed is MAPK8; the disease is liver disorder.