LBP has been shownto act as an endogenous inhibitor of dopamine β-hydroxylase(DBH) and aromatic l-amino acid decarboxylase (DDC), twokey enzymes involved in dopamine and serotonin synthesis., Given that dopaminergic dysfunction has been implicated in neuropsychiatricsymptoms, such as fatigue and cognitive impairment, the significantupregulation of LBP observed in our findings may contribute to post-COVIDneurological sequelae. Here, DBH is linked to Cognitive impairment.