ALDH1A1 and leukemia: Recently, Elcheva et al found that IGF2BP1 plays a vital role in drug metabolic processes, as it could sensitize leukemia cells to the alkylating agents by regulating the expression levels of aldehyde dehydrogenase 1A1 (ALDH1A1), a factor that promotes tumor glycolysis, in a post-transcriptional regulation way.168