Moreover, IGF2BP1 can recognize and bind to the mRNA of alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase (MGAT5), BUB1B, c-Myc, and IQ motif containing GTPase-activating protein 3 (IQGAP3) through m6A modification, thereby maintaining the stemness of HCC, NSCLC, and breast cancer stems cells.109. This evidence concerns the gene IQGAP3 and breast cancer.