EVPL and chronic myelogenous leukemia, BCR-ABL1 positive: The p210 BCR-ABL1 protein, encoded by either a b2a2 or b3a2 fusion transcript and possessing a molecular weight of 210 kDa, represents the prototypical fusion protein associated with chronic myeloid leukemia and serves as the molecular hallmark in the majority of chronic myeloid leukemia cases.