Sharma et al54 validated the synergistic effect of IGF2BP1 (insulin-like growth factor 2 mRNA binding protein 1) with ETV6-RUNX1 and revealed the role of IGF2BP1 through mRNA stabilization in the oncogenic process of B-cell acute lymphoblastic leukemia. The gene discussed is RUNX1; the disease is B-cell acute lymphoblastic leukemia.