Likewise, it has been suggested that the extra centrosome-associated secretory pathway (ECASP), which induces the release of several pro-invasive and SASP factors (such as growth differentiation factor 15 (GDF15) and IL-8), which are linked to tumorigenesis and tumor metastasis, may be responsible for these notable alterations.120. Here, CXCL8 is linked to neoplasm.