RFC1 and late-onset spinocerebellar ataxia 27b: However, in the last few years, intronic expansions in the RFC1 and FGF14 genes have been found in a number of the patients with late onset cerebellar ataxia (LOCA), respectively in the cerebellar ataxia neuropathy and vestibular areflexia syndrome (CANVAS) and SCA27B [55, 56, 57].