SGCE and Myoclonus: Myoclonus can also be associated with dystonia in the myoclonus-dystonia syndrome caused by variants in the SGCE gene (SGCE-MD), classically proximal, subcortical myoclonus with a characteristic “shivering” component, appendicular myoclonus, possible spasmodic dysphonia, a strong positive response to alcohol, and a history of anxiety and obsessive-compulsive disorders (OCD) (Supplementary Table 4).