SIRT1 and infection: Wehave previously shown that the intergenic interactions of theTP53, TP73, CDKN2A, and SIRT1 genes polymorphic lociaffect the risk of clinically significant viral load formation inHPV infection, which may be due to the influence on the cellcycle control and apoptosis processes (AlBosale, Mashkina,2022; Mashkina et al., 2023).