Meanwhile, a randomized controlled trial that used allogenic FMT from MetS donor (METS-D) feces versus feces from post-Roux-en-Y gastric bypass donor (RYGB-D) feces as a control group also demonstrated that transplantation using fecal microbiota from metabolically impaired obese donors also temporarily worsened insulin sensitivity in MetS recipients. The gene discussed is INS; the disease is metabolic syndrome.