This is important since Yap1 is also considered a pathological marker in various inflammatory diseases, including atherosclerosis (e.g., Yap1 suppression is connected to NLRP3 inflammasome inhibition[48]) and osseotendinous inflammation (e.g., Yap/Hippo pathway is linked to excessive tenascin[51]). This evidence concerns the gene TNC and atherosclerosis.