This finding is consistent with Yap1 expression profiles in patients with diabetic osteoarthritis and rheumatoid arthritis.[47, 48, 49, 50, 51, 52, 53] Notably, our animal‐product‐free synovial tissue construct closely matched human tissue in collagen type I, reticular collagen type III, and lubricin matrix expression. This evidence concerns the gene YAP1 and rheumatoid arthritis.