CD8A and neoplasm: Beyond CD8+ T cells, various other immune populations, including regulatory T cells (Tregs), myeloid‐derived suppressor cells (MDSCs), and tumor‐associated macrophages (TAMs), significantly shape the tumor immune microenvironment and influence immunotherapy efficacy.[73, 74] Future investigations should explore how mechanical cues such as cyclic stretch and ECM stiffness specifically modulate these additional cell subsets, further clarifying the comprehensive mechanotransductive landscape influencing tumor immunity.