The tumor tissues with both higher levels of PD‐L1 and more CD8+ T cell infiltration appear better immunotherapy response than that only with either higher PD‐L1 level or more CD8+ T infiltration.[69] In addition, simultaneous enhancement of the PD‐L1 expression and infiltration of CD8+ T cell has been applied to improve the immunotherapy response of tumor tissues,[70, 71] which is consistent with our observation (Figure 5b‐d). Here, CD8A is linked to neoplasm.