Phosphorylated TDP‐43 (pTDP‐43) is observed in approximately two‐thirds of AD brains.1,9 In this study, we demonstrated that TDP‐43 phosphorylation disrupts its binding to GAP43 cryptic exon 4a1 and induces aberrant GAP43 transcripts (Figure 4E). The gene discussed is TARDBP; the disease is Alzheimer disease.