MPO and chronic obstructive pulmonary disease: When administered to COPD rats, the Ber-loaded nanoparticles significantly reduced lung inflammation, levels of cytokines, and activities of Superoxide Dismutase (SOD) and Myeloperoxidase (MPO) enzymes in Bronchoalveolar Lavage Fluid (BALF), compared to pure berberine (Fig. 6) (Liu et al. 2022).