To further identify the correlation between promoter methylation and C1QL1 expression, we used Aza for demethylation on MDA-MB-231 and MDA-MB-468 cell lines, which showed relatively lower expression of C1QL1 than MCF-10A and other BrCa cell lines (Fig. 1g). Here, C1QL1 is linked to invasive breast carcinoma.