For example, compound heterozygous nonsynonymous TREX1 mutations were found in a patient with AGS who developed Hodgkin lymphoma, and decreased prevalence of the minor allele A of the nonsynonymous variant rs11797 (at TREX1b protein position Y177, Tables S7 and S8) was reported in patients with co-occurrence of the autoimmune disease primary Sjogren’s syndrome and MALT (the mainly mucosa associated lymphoid tissue lymphoma type), a type of non-Hodgkin lymphoma [118, 119]. This evidence concerns the gene TREX1 and Sjogren syndrome.