GRIN2B and brain injury: CRMP2 also interacts with GluN2B‐containing NMDARs (Bretin et al. 2006; Moutal et al. 2014), and disruption of those interactions reduces NMDAR‐mediated currents, providing neuroprotection in models of brain injury (Brittain et al. 2012; Brustovetsky et al. 2014).