She was a 61 years old patient with a 27 mm intra- and suprasellar macroadenoma, with typical stigmata and clinical symptoms of acromegaly that was confirmed endocrinologically (IGF-1: 640.0 ng/ml; hGH: 3.81 μg/L) and was in remission postoperatively (IGF-1: 135.0 ng/ml; hGH: 0.37 μg/L). The gene discussed is GH1; the disease is acromegaly.