Notably, we observed markers that have been suggested to play a role in treatment resistance but were not described in the concept of stemness in T-ALL, e.g., ADGRE5 (CD97)31, AHNAK32, CD2733, COL6A234, ITGB731, several members of the S100 family35 and the anti-apoptotic proteins BCL-6, BCL-2, BCL2L1/BCL-xL, and MCL1. This evidence concerns the gene MCL1 and acute lymphoblastic leukemia.