LCK and neoplasm: We find 161 genes that are affected by AS in samples of at least two patients, including known T-ALL oncogenes (e.g., LCK, MYB, FOS; detected in four patients) and tumor suppressors (e.g., PTPRC; detected in four patients), splicing factors (e.g., HNRNPH1; detected in six patients), ribosomal proteins (e.g., RPL32, RPL27A; detected in six and five patients), and epigenetic modifiers (e.g., BRD2; detected in three patients).