Nonetheless, the proportion of stem-like cells significantly differs among the subgroups and the type of relapse, being most frequent in those samples representing TAL1 patients (18.86% of TAL1 T-ALL cells) and type-2 relapses (15.41% of type-2 relapse T-ALL cells) (permutation test: FDR < 0.05, log2FD > 0.25) (Fig. 3f, g and Supplementary Fig. 3a, b), and less common in PDXs of TLX1 patients (2.56% of TLX1-driven T-ALL cells) and type-1 relapses (3.70% of type-1 relapse T-ALL cells). Here, TLX1 is linked to acute lymphoblastic leukemia.