,28 Also, shared somatic SNPs in BARD1, ATM, and BRCA1 genes were detected among the patients with breast cancer at much higher frequencies than predicted by Genome Aggregation Database population allele frequencies (AHN versus Genome Aggregation Database: BARD1 = 44% versus 1.4%, ATM = 31% versus 3.2%, BRCA1 = 22% versus 4.6%).27 The gene discussed is BRCA1; the disease is breast carcinoma.