Cytokine levels decreased for 6 of 9 assayed cytokines or the chemokine in the Chr7x3 AAB variant (IL-17a, IL-22, IL-5, IFN-γ, TNF-α, and IL-1β) and further decreased for all cytokines and the CXCL1 chemokine in the Chr7x3 ABB variant when compared to infection with Chr7x2 SC5314 (S3 Fig). This evidence concerns the gene IFNG and infection.