Among these, highly expressed HLA-B, ZC2HC1A, HMGCL, TSFM, FAM120B, TRAF3, and MTHFR were associated with an increased risk of MS, while highly expressed ICA1L and AUH were associated with a decreased risk of MS (Fig. 3B and SI Appendix, Fig. S2). Here, HMGCL is linked to myeloid sarcoma.