IDUA is responsible for the degradation of glycosaminoglycans heparan sulfate and dermatan sulfate, and, therefore, it is involved in pathways of glycosaminoglycan degradation (40), metabolic pathways (41), and lysosome function (42), which have been proven to play a pivotal role in MS development, underscoring IDUA as a promising potential target. This evidence concerns the gene IDUA and myeloid sarcoma.