Among the 586 gastric biopsy samples analyzed, IHC‐based Hp classification was successful in 577 cases (98%), yielding the following distribution: 302 cases (52%) were negative for infection, 102 cases (18%) had CagA(−) infection, 151 cases (26%) had Western‐type infection, and 22 cases (4%) had East Asian‐type infection. This evidence concerns the gene S100A8 and infection.