Quercetin has the capability to influence multiple signaling pathways, including the PI3K/Akt/mTOR and MAPK/ERK1/2 pathways, as documented in prior research [16], Moreover, it has demonstrated anti-tumor properties in various cancer types, such as ovarian cancer [17], esophageal cancer [18], and breast cancer [19]. The gene discussed is AKT1; the disease is esophageal cancer.