The findings suggest that the herbal compounds with strong TGF-β inhibitory effects, such as danshen, may be particularly effective in treating fibrosis in NAFLD/NASH [40]. Additionally, TNF-α inhibition by compounds like silymarin could help alleviate inflammation and slow down the progression to fibrosis [41]. Here, TGFB1 is linked to metabolic dysfunction-associated steatohepatitis.