ACEi, angiotensin-converting enzyme inhibitor; ARB, angiotensin II receptor blocker; BMI, body mass index; CAD, coronary artery disease; CCB, calcium-channel blocker; CKD, chronic kidney disease; eGFR, estimated glomerular filtration rate; MVC, maximal voluntary contraction; MMSE mini-mental state examination; UPCR, urinary protein-to-creatinine ratio. Here, ACE is linked to coronary artery disorder.