However, patients with spastic quadriplegia can present significant challenges for positioning and administering regional anesthesia. Catecholaminergic polymorphic ventricular tachycardia (CPVT) results from mutations in the RyR2 gene, leading to spontaneous calcium release from the sarcoplasmic reticulum in cardiac cells, which is characterized by syncopal episodes and sudden cardiac death [4,5]. This evidence concerns the gene RYR2 and catecholaminergic polymorphic ventricular tachycardia.