First-month T-cell lymphopenia (CD3+ hazard ratio [HR] 2.48, p=0.005; CD8+ HR 2.38, p=0.008) and hypogammaglobulinemia (IgG HR 2.18, p=0.036; IgA HR 2.40, p=0.011; IgM HR 2.61, p=0.006) were associated with higher risk of late infections. This evidence concerns the gene CD40LG and lymphopenia.