The most common grade 3 or 4 adverse events in the HTP and HT groups were neutropenia (17/175, 9.71% vs 1/76, 1.32%), elevated aspartate transaminase or alanine aminotransferase (17/175, 9.71% vs 6/76, 7.89%), thrombocytopenia (5/175, 2.86% vs 1/76,1.32%). Here, GPT is linked to neutropenia.