The most common adverse events observed in the HTP or HT group included elevated levels of aspartate transaminase or alanine aminotransferase (78/175, 44.57% vs 32/76, 42.11%), neutropenia (45/175, 25.71% vs 9/76, 11.84%), thrombocytopenia (52/175, 29.71% vs 22/76, 28.95%), hypoalbuminemia (37/175, 21.14% vs 16/76, 21.05%) and elevated bilirubin (20/175, 11.43% vs 6/76, 7.89%). The gene discussed is GPT; the disease is Decreased total neutrophil count.