Furthermore, in advanced HCC, another study reported that the TACE+LEN+PD-1 group achieved a PFS of 7.3 months and an OS of 16.9 months, outperforming the TACE+LEN group (PFS: 4.0 months, OS: 12.1 months) (13). Here, PDCD1 is linked to hepatocellular carcinoma.