In vitroTHP-1 and HER2+ K562 cellsHER2+ beadsTHP-1 and HER2+ SKOV3 ovarian cancer cellsIn vivoNSGS mice with primary human macrophages and HER2+SKOV3 tumor model (I.V or I.P injected)Phase I Clinical trialCT-0508. 14 patients with breast and gastroesophageal tumors. The gene discussed is ERBB2; the disease is neoplasm.