Triple immunolabeling with inner retina cell type-specific antibodies – against CHX10 (officially known as VSX2) to identify all bipolar (BC) cells, against ISL1 to identify ON-bipolar cells or against PKC-α (officially known as PKCA) to identify rod bipolar cells (RBCs) (see also Table 1) – were used to assess the integrity of these cell populations. This evidence concerns the gene ISL1 and breast cancer.