In the univariable analysis, in addition to the severity of thinness, male sex, diabetes mellitus, estimated glomerular filtration rate, hemodialysis, albumin, hemoglobin, hypertension, chronic obstructive pulmonary disease, immunosuppressant drugs, peripheral artery disease, cerebrovascular disease, malignant disease, liver cirrhosis, New York Heart Association (NYHA), atrial fibrillation, LVEF, mean pressure gradient (PG), STS-PROM, elective surgery, TF approach and PPM ≥ moderate were associated with P < 0.1 (Supplementary Table S4). This evidence concerns the gene ALB and chronic obstructive pulmonary disease.