Next, poly(I:C) (which can stimulate TLR3), different CpG ODNs (types A, B, and C), GM‐CSF, Bacillus Calmette–Guérin (BCG), and STING agonists, or their combinations, were co‐encapsulated with tumor antigens into NVs/MVs. This evidence concerns the gene CSF2 and neoplasm.