TLR9 and melanoma: WDVAX is melanoma cell lysate administered with cytokine Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) and the innate toll-like receptor 9 agonist CpG oligonucleotide onto a matrix polymer scaffold that allows for precise control of the immunostimulatory agents and stimulation of dendritic cell maturation [34].