Two important clinical examples of this subgroup are a protein vaccine targeting the parathyroid hormone-related protein (PTHrP) in hypercalcemic solid tumors, and a combination of cancer peptides, called TAS0313, derived from eight disregulated cancer genes (EGFR, KUA, LCK, MRP3, PTHRP, SART2, SART3, and WHSC2) in glioblastoma [49]. The gene discussed is PEDS1; the disease is cancer.