ACHE and early-onset autosomal dominant Alzheimer disease: In the present study, the H. repens hydroethanolic extract exhibited very mild anticholinesterase activity in the AChE and BChE inhibition assays, indicating a relatively weak ability to interfere with these enzymes’ activity, when compared to the positive control donepezil, a well-known cholinesterase inhibitor employed in Alzheimer’s disease treatment [31].