In addition, hypoxia present within the tumor niche stimulates the transcription and production of PGF, which promotes the homing of MSCs at the tumor site and the production of different chemokines (such as CXCL10 and CCL5) that have paracrine action on CSCs, promoting their progression and motility [45,46,47]. The gene discussed is CXCL10; the disease is neoplasm.