After drug treatment for 8 weeks, all of these indicators were markedly improved the in BZYQF-treated rats compared with those in T2DM rats, including FBG (p = 0.0058), TC (p < 0.0001), TG (p < 0.0001), insulin (p = 0.0017), and HOMA-β (p = 0.0106), and similar results were found in the metformin-treated rats. The gene discussed is INS; the disease is type 2 diabetes mellitus.