A comprehensive review designed to inform clinical guidelines for von Willebrand disease (VWD), suggests that maintaining factor VIII (FVIII) and vWF levels above 0.50 IU/mL for a minimum of three days post-surgery can lead to effective haemostasis, which was deemed excellent by the researchers in 74–100% of the surgeries analysed [38]. This evidence concerns the gene VWF and platelet-type von Willebrand disease.