The results demonstrated a marked upregulation of CBX1 expression in LIHC as well as in various cancers, such as cholangiocarcinoma, diffuse large B-cell lymphoma, lung squamous cell carcinoma, pancreatic adenocarcinoma, pheochromocytoma, paraganglioma, and thymoma (Figure 1A). The gene discussed is CBX1; the disease is hereditary pheochromocytoma-paraganglioma.