Notably, the classification of high-grade B-cell lymphoma characterised by dual rearrangements involving MYC and either BCL2 or BCL6 has been redefined as DLBCL with high-grade B-cell lymphoma with MYC/BCL2 (DLBCL/HGBL-MYC/BCL2). The gene discussed is BCL2; the disease is B-cell non-Hodgkin lymphoma.