Similar results were also reported by Förster et al. [8], on both natural hvPLA2 and recombinant PLA2 produced in Escherichia coli. In the same line, it has been shown that most individuals with HBV allergy (96%) also react to the recombinant PLA2 produced in Escherichia coli [146]. This evidence concerns the gene PLA2G5 and Allergy.